Whole genome resequencing of a laboratory-adapted Drosophila melanogaster
نویسندگان
چکیده
منابع مشابه
Whole genome resequencing of a laboratory-adapted Drosophila melanogaster population sample
As part of a study into the molecular genetics of sexually dimorphic complex traits, we used next-generation sequencing to obtain data on genomic variation in an outbred laboratory-adapted fruit fly (Drosophila melanogaster) population. We successfully resequenced the whole genome of 220 hemiclonal females that were heterozygous for the same Berkeley reference line genome (BDGP6/dm6), and a uni...
متن کاملWhole genome resequencing of a laboratory - adapted population sample
As part of a study into the molecular genetics of sexually dimorphic complex traits, we used next-generation sequencing to obtain data on genomic variation in an outbred laboratory-adapted fruit fly (Drosophila melanogaster) population. We successfully resequenced the whole genome of 220 hemiclonal females that were heterozygous for the same Berkeley reference line genome (BDGP6/dm6), and a uni...
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Complete genome resequencing of populations holds great promise in deconstructing complex polygenic traits to elucidate molecular and developmental mechanisms of adaptation. Egg size is a classic adaptive trait in insects, birds, and other taxa, but its highly polygenic architecture has prevented high-resolution genetic analysis. We used replicated experimental evolution in Drosophila melanogas...
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Transposable elements are mobile DNA sequences that integrate into host genomes using diverse mechanisms with varying degrees of target site specificity. While the target site preferences of some engineered transposable elements are well studied, the natural target preferences of most transposable elements are poorly characterized. Using population genomic resequencing data from 166 strains of ...
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Drosophila melanogaster is an established model organism for the study of host-pathogen interactions. The sequencing of its genome allowed the prediction of all the genes encoded in it and, consequently, enabled a more comprehensive view of its immune responses. Whole-genome transcription analyses of Drosophila response to bacteria, fungi, parasitoids and viruses allow a comparison of the respo...
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ژورنال
عنوان ژورنال: F1000Research
سال: 2016
ISSN: 2046-1402
DOI: 10.12688/f1000research.9912.2